Definition:Skewes' Number/Historical Note

Historical Note on Skewes' Number
deduced the number which now bears his name in $1933$.

referred to it as:
 * the largest number which has ever served any definite purpose in mathematics.

By way of comparison, the number of particles in the universe has been estimated at somewhere between $10^{80}$ and $10^{87}$.

However, estimate has been reduced somewhat more recently.

For example, has shown that there are many $n$ between $6 \cdotp 62 \times 10^{370}$ and $6 \cdotp 69 \times 10^{370}$ for which $\pi \left({n}\right)$ is less than $\displaystyle \int_2^n \frac {\mathrm d x} {\ln x}$.